Vaccinia Virus A34 Glycoprotein Determines the Protein

Viral Glycoproteins The Pirbright Institute

The interaction between virus particles and host cells is often determined by the specific affinities of viral attachment proteins for their host receptors.The nature,strength and specificity of these interactions plays an important role in determining the mechanisms of particle entry as well as the host range and cell-specificity (tropism Vaccinia virus morphogenesis and dissemination Trends in Vaccinia virus is the smallpox vaccine.It is the most intensively studied poxvirus,and its study has provided important insights about virus replication in general and the interactions of viruses with the host cell and immune system.Here,the entry,morphogenesis and dissemination of vaccinia virus are considered.These processes are complicated by the existence of two infectious vaccinia Vaccinia virus morphogenesis and dissemination -Oct 01,2008 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;B.Perdiguero,et al.Vaccinia virus A34 glycoprotein determines the protein composition of the extracellular virus envelope J.Virol.,82 (2008),pp.2150-2160 Google Scholar

Vaccinia Virus Glycoproteins A33,A34,and B5 Form a

Vaccinia Virus Glycoproteins A33,A34,and B5 Form a Complex for Efficient Endoplasmic Reticulum to trans-Golgi Network Transport J Virol .2020 Mar 17;94(7):e02155-19.doi 10.1128/JVI.02155-19.Vaccinia Virus A34 Glycoprotein Determines the Protein The outer envelope of the extracellular form of vaccinia virus contains five virus-encoded proteins,F13,A33,A34,A56,and B5,that,with the exception of A56,are implicated in virus egress or infectivity.A34,a type II transmembrane glycoprotein,Vaccines inducing immunity to Lassa virus glycoprotein and Thousands of people in Western Africa succumb to Lassa fever each year.Lassa virus infections can in some cases respond to antiviral treatment,but there is no vaccine.Mateo et al.tested three different viral-vectored Lassa virus vaccines in a nonhuman primate model.They compared transcriptomic and proteomic signatures as well as B cell and T cell responses after vaccination.

VACWR157 - Protein A34 - Vaccinia virus (strain Western

Mar 01,1992 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Protein A34.Gene.VACWR157.Organism.Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) Status.Reviewed-Annotation score -Experimental Glycoprotein Proteomic databases PRIDE i P24761 Interaction i Transport and stability of the vaccinia virus A34 protein Transport and stability of the vaccinia virus A34 protein is affected by the A33 protein.pdf. A34 glycoprotein determines the protein composition of the.extracellular virus envelope.Structure of RSV Fusion Glycoprotein Trimer Bound to a May 31,2013 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Vaccines are one of the most effective tools to protect against infectious diseases.Unfortunately,vaccines for diseases with the highest global health burdens,such as HIV,malaria,and tuberculosis,are not yet available.Koff et al.(p.[1064][1]) review the latest advances in vaccine development and why these particular diseases remain such a challenge.Respiratory syncytial virus

Some results are removed in response to a notice of local law requirement.For more information,please see here.Short Vaccinia virus B5 protein affects the

Vaccinia virus B5 protein affects the glycosylation,localization and stability of the A34 protein Adrien Breiman and Geoffrey L.Smith Correspondence Geoffrey L.Smith [email protected]Short Vaccinia virus B5 protein affects theVaccinia virus B5 protein affects the glycosylation,localization and stability of the A34 protein Adrien Breiman and Geoffrey L.Smith Correspondence Geoffrey L.Smith [email protected]

Processing of the Ebola virus glycoprotein by the

In the present study,we have investigated processing and maturation of the envelope glycoprotein (GP) of Ebola virus.When GP expressed from vaccinia virus vectors was analyzed by pulsechase experiments,the mature form and two different precursors were identified.First,the endoplasmic reticulum form preGPer,full-length GP with oligomannosidic N -glycans,was detected.preGPer (110Previous123456NextTransport and stability of the vaccinia virus A34 protein Transport and stability of the vaccinia virus A34 protein is affected by the A33 protein.pdf. A34 glycoprotein determines the protein composition of the.extracellular virus envelope.Partial Deletion of Glycoprotein B5R Enhances Vaccinia Vaccinia virus (VV) has been utilized in oncolytic virotherapy,but it risks a host antiviral immune response.VV has an extracellular enveloped virus (EEV) form consisting of a normal virion covered with a host-derived outer membrane that enables its spread via circulation while evading host immune mechanisms.However,the immune resistance of EEV is only partial,owing to expression of the

Partial Deletion of Glycoprotein B5R Enhances Vaccinia

Vaccinia virus (VV) has been utilized in oncolytic virotherapy,but it risks a host antiviral immune response.VV has an extracellular enveloped virus (EEV) form consisting of a normal virion covered with a host-derived outer membrane that enables its spread via circulation while evading host immune mechanisms.However,the immune resistance of EEV is only partial,owing to expression of the Partial Deletion of Glycoprotein B5R Enhances Vaccinia Sep 27,2019 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Vaccinia virus (VV) can escape antiviral immunity using a unique infectious formnamely,the extracellular enveloped virus (EEV).9 Most progeny virions mature as the normal infectious form,intracellular mature virus (IMV),and are released after host cell death; however,a few are covered with or wrapped in early endosomes or a trans-Golgi Partial Deletion of Glycoprotein B5R Enhances Vaccinia Sep 27,2019 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Vaccinia virus (VV) can escape antiviral immunity using a unique infectious formnamely,the extracellular enveloped virus (EEV).9 Most progeny virions mature as the normal infectious form,intracellular mature virus (IMV),and are released after host cell death; however,a few are covered with or wrapped in early endosomes or a trans-Golgi

PS/HR - Protein B5 precursor - Vaccinia virus (strain

Protein sets from fully sequenced genomes. Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) Status.Reviewed-Annotation score -Experimental Interacts with A34; this interaction is required for the correct glycosylation,trafficking and stability of A34 and B5 incorporation into extracellular enveloped virionsInteraction between vaccinia virus extracellular virus The extracellular form of vaccinia virus acquires its outer envelope by wrapping with cytoplasmic membranes that contain at least seven virus-encoded proteins,of which four are glycoproteins.We searched for interactions between the vaccinia virus A33 glycoprotein and proteins A34Interaction between vaccinia virus extracellular virus The extracellular form of vaccinia virus acquires its outer envelope by wrapping with cytoplasmic membranes that contain at least seven virus-encoded proteins,of which four are glycoproteins.We searched for interactions between the vaccinia virus A33 glycoprotein and proteins A34

Interaction between Vaccinia Virus Extracellular Virus

interactions between the vaccinia virus A33 glycoprotein and proteins A34,A36,B5,F12,and F13.First,when myc epitope-tagged A33 was expressed in combination with other envelope proteins,A33 Human immunodeficiency virus envelope protein determines In polarized epithelial cells,the release of enveloped viruses by budding at the cell surface is restricted to a specific cell membrane domain,either the apical or basolateral domain.To investigate the role of the envelope glycoprotein and the capsid proteins of human immunodeficiency virus type 1 (HIV-1) in determining the site of virus assembly,we analyzed virus maturation in a polarized Experimental respiratory syncytial virus vaccine prompts Aug 01,2019 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;To do this,they first determined the atomic-level structure of a surface protein,fusion (F) glycoprotein,in its rearranged postfusion and functional prefusion states.The prefusion state displays the epitopes best able to elicit strong-binding neutralizing antibodies,but those epitopes are lost once the F protein changes into the

Cited by 23Publish Year 2008Author Beatriz Perdiguero,Mar Vaccinia Virus A34 Glycoprotein Determines the Protein#237;a M.Lorenzo,Rafael BlascoVaccinia virus A34 glycoprotein determines the protein

Dec 19,2007 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Construction of a recombinant vaccinia virus expressing HA-tagged A34 protein.To facilitate experiments on interactions involving glycoprotein A34,a modified version of the protein (A34 HA) was obtained by fusing an epitope tag derived fromCited by 23Publish Year 2008Author Beatriz Perdiguero,Mar Vaccinia Virus A34 Glycoprotein Determines the Protein#237;a M.Lorenzo,Rafael BlascoImages of Vaccinia Virus A34 Glycoprotein Determines the Pr imagesVaccinia Virus A34 Glycoprotein Determines the Protein Vaccinia Virus A34 Glycoprotein Determines the Protein Composition of the Extracellular Virus Envelope Extracts of BSC-1 cells infected for 24 h with a recombinant vaccinia virus expressing CiteSeerX Interaction between Vaccinia Virus CiteSeerX - Document Details (Isaac Councill,Lee Giles,Pradeep Teregowda) The extracellular form of vaccinia virus acquires its outer envelope by wrapping with cytoplasmic mem-branes that contain at least seven virus-encoded proteins,of which four are glycoproteins.We searched for interactions between the vaccinia virus A33 glycoprotein and proteins A34,A36,B5,F12,and F13.

Adsorption Experiments with the Virus of Vaccinia

Vaccinia virus A34 glycoprotein determines the protein composition of the extracellular virus envelope.Perdiguero B,Lorenzo MM,Blasco R.J Virol,82(5):2150-2160,19 Dec 2007 Cited by 18 articles PMID 18094186 PMCID PMC2258926.Free to readAdsorption Experiments with the Virus of Vaccinia Vaccinia virus A34 glycoprotein determines the protein composition of the extracellular virus envelope.Perdiguero B,Lorenzo MM,Blasco R.J Virol,82(5):2150-2160,19 Dec 2007 Cited by 18 articles PMID 18094186 PMCID PMC2258926.Free to readAcidic residues in the membrane-proximal stalk region of Vaccinia virus A34 glycoprotein determines the protein composition of the extracellular virus envelope.J Virol 82 ,21502160.[ PMC free article ] [ PubMed ]

A34R - Protein A34 - Variola virus (isolate Human/India

Protein knowledgebase.UniParc.Sequence archive.Help.Help pages,FAQs,UniProtKB manual,documents,news archive and Biocuration projects.UniRef.Sequence clusters.Proteomes.Protein sets from fully sequenced genomes.Annotation systems.Systems used to automatically annotate proteins with high accuracy UniRule (Expertly curated rules)A34R - Protein A34 - Vaccinia virus (strain Copenhagen Protein A34.Gene.A34R.Organism.Vaccinia virus (strain Copenhagen) (VACV) Status.Reviewed-Annotation score -Protein inferred from homology i.Function i.Required for the envelopment of intracellular viral particles and egress of enveloped virions from the infected cell.A34R - Protein A34 - Vaccinia virus (strain Copenhagen Protein A34.Gene.A34R.Organism.Vaccinia virus (strain Copenhagen) (VACV) Status.Reviewed-Annotation score -Protein inferred from homology i.Function i.Required for the envelopment of intracellular viral particles and egress of enveloped virions from the infected cell.

12345NextVaccinia Virus Glycoproteins A33,A34,and B5 Form a

Vaccinia Virus Glycoproteins A33,A34,and B5 Form a Complex for Efficient Endoplasmic Reticulum to trans-Golgi Network Transport J Virol .2020 Mar 17;94(7):e02155-19.doi 10.1128/JVI.02155-19.(PDF) Vaccinia virus B5 protein affects the glycosylation The vaccinia virus strain Western Reserve (WR) A34R gene encodes a C-type lectin-like glycoprotein,gp22-24,that is present in the outer membrane of extracellular enveloped virus (EEV) with type

Viral Glycoproteins The Pirbright Institute

The interaction between virus particles and host cells is often determined by the specific affinities of viral attachment proteins for their host receptors.The nature,strength and specificity of these interactions plays an important role in determining the mechanisms of particle entry as well as the host range and cell-specificity (tropism Vaccinia virus morphogenesis and dissemination Trends in Vaccinia virus is the smallpox vaccine.It is the most intensively studied poxvirus,and its study has provided important insights about virus replication in general and the interactions of viruses with the host cell and immune system.Here,the entry,morphogenesis and dissemination of vaccinia virus are considered.These processes are complicated by the existence of two infectious vaccinia Vaccinia virus morphogenesis and dissemination -Oct 01,2008 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;B.Perdiguero,et al.Vaccinia virus A34 glycoprotein determines the protein composition of the extracellular virus envelope J.Virol.,82 (2008),pp.2150-2160 Google Scholar

Vaccinia Virus Glycoproteins A33,A34,and B5 Form a

Vaccinia Virus Glycoproteins A33,A34,and B5 Form a Complex for Efficient Endoplasmic Reticulum to trans-Golgi Network Transport J Virol .2020 Mar 17;94(7):e02155-19.doi 10.1128/JVI.02155-19.Vaccinia Virus A34 Glycoprotein Determines the Protein The outer envelope of the extracellular form of vaccinia virus contains five virus-encoded proteins,F13,A33,A34,A56,and B5,that,with the exception of A56,are implicated in virus egress or infectivity.A34,a type II transmembrane glycoprotein,Vaccines inducing immunity to Lassa virus glycoprotein and Thousands of people in Western Africa succumb to Lassa fever each year.Lassa virus infections can in some cases respond to antiviral treatment,but there is no vaccine.Mateo et al.tested three different viral-vectored Lassa virus vaccines in a nonhuman primate model.They compared transcriptomic and proteomic signatures as well as B cell and T cell responses after vaccination.

VACWR157 - Protein A34 - Vaccinia virus (strain Western

Mar 01,1992 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Protein A34.Gene.VACWR157.Organism.Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) Status.Reviewed-Annotation score -Experimental Glycoprotein Proteomic databases PRIDE i P24761 Interaction i Transport and stability of the vaccinia virus A34 protein Transport and stability of the vaccinia virus A34 protein is affected by the A33 protein.pdf. A34 glycoprotein determines the protein composition of the.extracellular virus envelope.Structure of RSV Fusion Glycoprotein Trimer Bound to a May 31,2013 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Vaccines are one of the most effective tools to protect against infectious diseases.Unfortunately,vaccines for diseases with the highest global health burdens,such as HIV,malaria,and tuberculosis,are not yet available.Koff et al.(p.[1064][1]) review the latest advances in vaccine development and why these particular diseases remain such a challenge.Respiratory syncytial virus

Some results are removed in response to a notice of local law requirement.For more information,please see here.Short Vaccinia virus B5 protein affects the

Vaccinia virus B5 protein affects the glycosylation,localization and stability of the A34 protein Adrien Breiman and Geoffrey L.Smith Correspondence Geoffrey L.Smith [email protected]Short Vaccinia virus B5 protein affects theVaccinia virus B5 protein affects the glycosylation,localization and stability of the A34 protein Adrien Breiman and Geoffrey L.Smith Correspondence Geoffrey L.Smith [email protected]

Processing of the Ebola virus glycoprotein by the

In the present study,we have investigated processing and maturation of the envelope glycoprotein (GP) of Ebola virus.When GP expressed from vaccinia virus vectors was analyzed by pulsechase experiments,the mature form and two different precursors were identified.First,the endoplasmic reticulum form preGPer,full-length GP with oligomannosidic N -glycans,was detected.preGPer (110Previous123456NextTransport and stability of the vaccinia virus A34 protein Transport and stability of the vaccinia virus A34 protein is affected by the A33 protein.pdf. A34 glycoprotein determines the protein composition of the.extracellular virus envelope.Partial Deletion of Glycoprotein B5R Enhances Vaccinia Vaccinia virus (VV) has been utilized in oncolytic virotherapy,but it risks a host antiviral immune response.VV has an extracellular enveloped virus (EEV) form consisting of a normal virion covered with a host-derived outer membrane that enables its spread via circulation while evading host immune mechanisms.However,the immune resistance of EEV is only partial,owing to expression of the

Partial Deletion of Glycoprotein B5R Enhances Vaccinia

Vaccinia virus (VV) has been utilized in oncolytic virotherapy,but it risks a host antiviral immune response.VV has an extracellular enveloped virus (EEV) form consisting of a normal virion covered with a host-derived outer membrane that enables its spread via circulation while evading host immune mechanisms.However,the immune resistance of EEV is only partial,owing to expression of the Partial Deletion of Glycoprotein B5R Enhances Vaccinia Sep 27,2019 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Vaccinia virus (VV) can escape antiviral immunity using a unique infectious formnamely,the extracellular enveloped virus (EEV).9 Most progeny virions mature as the normal infectious form,intracellular mature virus (IMV),and are released after host cell death; however,a few are covered with or wrapped in early endosomes or a trans-Golgi Partial Deletion of Glycoprotein B5R Enhances Vaccinia Sep 27,2019 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Vaccinia virus (VV) can escape antiviral immunity using a unique infectious formnamely,the extracellular enveloped virus (EEV).9 Most progeny virions mature as the normal infectious form,intracellular mature virus (IMV),and are released after host cell death; however,a few are covered with or wrapped in early endosomes or a trans-Golgi

PS/HR - Protein B5 precursor - Vaccinia virus (strain

Protein sets from fully sequenced genomes. Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) Status.Reviewed-Annotation score -Experimental Interacts with A34; this interaction is required for the correct glycosylation,trafficking and stability of A34 and B5 incorporation into extracellular enveloped virionsInteraction between vaccinia virus extracellular virus The extracellular form of vaccinia virus acquires its outer envelope by wrapping with cytoplasmic membranes that contain at least seven virus-encoded proteins,of which four are glycoproteins.We searched for interactions between the vaccinia virus A33 glycoprotein and proteins A34Interaction between vaccinia virus extracellular virus The extracellular form of vaccinia virus acquires its outer envelope by wrapping with cytoplasmic membranes that contain at least seven virus-encoded proteins,of which four are glycoproteins.We searched for interactions between the vaccinia virus A33 glycoprotein and proteins A34

Interaction between Vaccinia Virus Extracellular Virus

interactions between the vaccinia virus A33 glycoprotein and proteins A34,A36,B5,F12,and F13.First,when myc epitope-tagged A33 was expressed in combination with other envelope proteins,A33 Human immunodeficiency virus envelope protein determines In polarized epithelial cells,the release of enveloped viruses by budding at the cell surface is restricted to a specific cell membrane domain,either the apical or basolateral domain.To investigate the role of the envelope glycoprotein and the capsid proteins of human immunodeficiency virus type 1 (HIV-1) in determining the site of virus assembly,we analyzed virus maturation in a polarized Experimental respiratory syncytial virus vaccine prompts Aug 01,2019 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;To do this,they first determined the atomic-level structure of a surface protein,fusion (F) glycoprotein,in its rearranged postfusion and functional prefusion states.The prefusion state displays the epitopes best able to elicit strong-binding neutralizing antibodies,but those epitopes are lost once the F protein changes into the

Cited by 23Publish Year 2008Author Beatriz Perdiguero,Mar Vaccinia Virus A34 Glycoprotein Determines the Protein#237;a M.Lorenzo,Rafael BlascoVaccinia virus A34 glycoprotein determines the protein

Dec 19,2007 Vaccinia Virus A34 Glycoprotein Determines the Protein#0183;Construction of a recombinant vaccinia virus expressing HA-tagged A34 protein.To facilitate experiments on interactions involving glycoprotein A34,a modified version of the protein (A34 HA) was obtained by fusing an epitope tag derived fromCited by 23Publish Year 2008Author Beatriz Perdiguero,Mar Vaccinia Virus A34 Glycoprotein Determines the Protein#237;a M.Lorenzo,Rafael BlascoImages of Vaccinia Virus A34 Glycoprotein Determines the Pr imagesVaccinia Virus A34 Glycoprotein Determines the Protein Vaccinia Virus A34 Glycoprotein Determines the Protein Composition of the Extracellular Virus Envelope Extracts of BSC-1 cells infected for 24 h with a recombinant vaccinia virus expressing CiteSeerX Interaction between Vaccinia Virus CiteSeerX - Document Details (Isaac Councill,Lee Giles,Pradeep Teregowda) The extracellular form of vaccinia virus acquires its outer envelope by wrapping with cytoplasmic mem-branes that contain at least seven virus-encoded proteins,of which four are glycoproteins.We searched for interactions between the vaccinia virus A33 glycoprotein and proteins A34,A36,B5,F12,and F13.

Adsorption Experiments with the Virus of Vaccinia

Vaccinia virus A34 glycoprotein determines the protein composition of the extracellular virus envelope.Perdiguero B,Lorenzo MM,Blasco R.J Virol,82(5):2150-2160,19 Dec 2007 Cited by 18 articles PMID 18094186 PMCID PMC2258926.Free to readAdsorption Experiments with the Virus of Vaccinia Vaccinia virus A34 glycoprotein determines the protein composition of the extracellular virus envelope.Perdiguero B,Lorenzo MM,Blasco R.J Virol,82(5):2150-2160,19 Dec 2007 Cited by 18 articles PMID 18094186 PMCID PMC2258926.Free to readAcidic residues in the membrane-proximal stalk region of Vaccinia virus A34 glycoprotein determines the protein composition of the extracellular virus envelope.J Virol 82 ,21502160.[ PMC free article ] [ PubMed ]

A34R - Protein A34 - Variola virus (isolate Human/India

Protein knowledgebase.UniParc.Sequence archive.Help.Help pages,FAQs,UniProtKB manual,documents,news archive and Biocuration projects.UniRef.Sequence clusters.Proteomes.Protein sets from fully sequenced genomes.Annotation systems.Systems used to automatically annotate proteins with high accuracy UniRule (Expertly curated rules)A34R - Protein A34 - Vaccinia virus (strain Copenhagen Protein A34.Gene.A34R.Organism.Vaccinia virus (strain Copenhagen) (VACV) Status.Reviewed-Annotation score -Protein inferred from homology i.Function i.Required for the envelopment of intracellular viral particles and egress of enveloped virions from the infected cell.A34R - Protein A34 - Vaccinia virus (strain Copenhagen Protein A34.Gene.A34R.Organism.Vaccinia virus (strain Copenhagen) (VACV) Status.Reviewed-Annotation score -Protein inferred from homology i.Function i.Required for the envelopment of intracellular viral particles and egress of enveloped virions from the infected cell.

12345NextVaccinia Virus Glycoproteins A33,A34,and B5 Form a

Vaccinia Virus Glycoproteins A33,A34,and B5 Form a Complex for Efficient Endoplasmic Reticulum to trans-Golgi Network Transport J Virol .2020 Mar 17;94(7):e02155-19.doi 10.1128/JVI.02155-19.(PDF) Vaccinia virus B5 protein affects the glycosylation The vaccinia virus strain Western Reserve (WR) A34R gene encodes a C-type lectin-like glycoprotein,gp22-24,that is present in the outer membrane of extracellular enveloped virus (EEV) with type

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